Tirzepatide vs Semaglutide: Differences and What to Track
Comparing tirzepatide (Mounjaro, Zepbound) and semaglutide (Wegovy, Ozempic)? Here is a tracking-focused guide — not prescribing advice.

Tirzepatide vs semaglutide is one of the most common comparison searches in the GLP-1 space — Mounjaro/Zepbound on one side, Wegovy/Ozempic on the other.
The basics
| | Tirzepatide | Semaglutide | |---|---|---| | Common brands | Mounjaro, Zepbound | Wegovy, Ozempic | | Typical schedule | Weekly injection | Weekly injection (most weight-loss pens) | | What users track | Dose, appetite, weight, side effects | Same |
This is not guidance on which medication to choose. In the UK, NICE guidance on tirzepatide and semaglutide sets NHS eligibility — your prescriber decides what is appropriate for you.
What to track on either medication
- Injection date and dose strength
- Titration steps over months
- Appetite and cravings
- Weekly weight trends
- Side effects with dates
Having one app for the full picture beats switching trackers if your medication changes.
Track your GLP-1 journey with GLPPal
GLPPal helps you log injections, appetite, weight and side effects in one calm app — built for Mounjaro, Zepbound, Wegovy and other GLP-1 users.
Sources
- Tirzepatide (Mounjaro) — NHS
- Semaglutide (Wegovy, Ozempic) — NHS
- GLP-1 medicines for weight loss and diabetes — MHRA (GOV.UK)
GLPPal is designed for tracking and educational purposes only and is not medical advice. Always follow your healthcare provider's guidance.