See how estimated semaglutide or tirzepatide levels rise and fall between weekly injections — and why appetite can return before your next dose.
Half-life
~5 days
Relative level now
100%
Day in weekly cycle
Day 1 of 7
Dashed lines mark weekly injection days. Levels build over the first few weeks then stabilise into a repeating weekly rhythm — many users report stronger appetite suppression mid-week and more hunger toward day 6–7. This is an educational model, not a clinical blood level.
Chart ends Sun, 13 Sept 2026 · Brands: Mounjaro, Zepbound
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Suggested citation: GLP-1 Medication Level Chart — www.glppal.app/tools/medication-level-chart
After each weekly injection, GLP-1 medication levels in your body gradually decline until the next dose. Semaglutide has a half-life of about 7 days; tirzepatide about 5 days. This means many people feel strongest appetite suppression mid-week and notice hunger returning toward day 6 or 7 — a normal pharmacological pattern, not a sign the medication stopped working.
Select semaglutide (Wegovy/Ozempic) or tirzepatide (Mounjaro/Zepbound).
Enter your dose and first injection date.
Watch how estimated relative levels build over the first weeks, then stabilise.
Track your real-world appetite and side effects alongside this in GLPPal.
No. This chart uses a simplified half-life model for education only. Real concentrations vary by person, injection site, and other factors. It illustrates the weekly cycle pattern many users report.
Download on the App Store. Log injections, appetite, weight and side effects — with reminders and weekly pattern insights.
GLPPal is designed for tracking and educational purposes only and is not medical advice.