GLP-1 Medication Level Chart

See how estimated semaglutide or tirzepatide levels rise and fall between weekly injections — and why appetite can return before your next dose.

0%25%50%75%100%Days since first injection

Half-life

~5 days

Relative level now

100%

Day in weekly cycle

Day 1 of 7

Dashed lines mark weekly injection days. Levels build over the first few weeks then stabilise into a repeating weekly rhythm — many users report stronger appetite suppression mid-week and more hunger toward day 6–7. This is an educational model, not a clinical blood level.

Chart ends Sun, 13 Sept 2026 · Brands: Mounjaro, Zepbound

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What is a medication level chart?

After each weekly injection, GLP-1 medication levels in your body gradually decline until the next dose. Semaglutide has a half-life of about 7 days; tirzepatide about 5 days. This means many people feel strongest appetite suppression mid-week and notice hunger returning toward day 6 or 7 — a normal pharmacological pattern, not a sign the medication stopped working.

How to read the medication level chart

  1. 1

    Select semaglutide (Wegovy/Ozempic) or tirzepatide (Mounjaro/Zepbound).

  2. 2

    Enter your dose and first injection date.

  3. 3

    Watch how estimated relative levels build over the first weeks, then stabilise.

  4. 4

    Track your real-world appetite and side effects alongside this in GLPPal.

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Medication Level Chart FAQ

No. This chart uses a simplified half-life model for education only. Real concentrations vary by person, injection site, and other factors. It illustrates the weekly cycle pattern many users report.

Track your full GLP-1 journey in GLPPal

Download on the App Store. Log injections, appetite, weight and side effects — with reminders and weekly pattern insights.

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GLPPal is designed for tracking and educational purposes only and is not medical advice.